In Spy Kids, Gregorio's children believe that he is a boring suburban father, until he and his wife get kidnapped by Fegan Floop and their children must save them. In the end of the film, when his brother Machete agrees to help save him, they renounce their conflict and hug.
Spy Kids 2: The Island of Lost Dreams
Spy Kids 3D: Game Over
Gregorio is the father of Juni Cortez
Gregorio is the father of Carmen Cortez
Gregorio is the husband of Ingrid Cortez.
Isador "Machete" Cortez
He also has a brother called Machete who he has a great deal of conflict with.
As well as this, he has a sister, Marissa, who has a daughter, Maria, and two step-children, Rebecca and Cecil Wilson. It is unknown what their interactions are, but it's presumed that he loved his sister dearly.